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首页> 外文OA文献 >Handheld probe integrating laser diode and ultrasound transducer array for ultrasound/photoacoustic dual modality imaging
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Handheld probe integrating laser diode and ultrasound transducer array for ultrasound/photoacoustic dual modality imaging

机译：集成了激光二极管和超声换能器阵列的手持式探头，用于超声/光声双模态成像

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Ultrasound and photoacoustics can be utilized as complementary imaging techniques to improve clinical diagnoses. Photoacoustics provides optical contrast and functional information while ultrasound provides structural and anatomical information. As of yet, photoacoustic imaging uses large and expensive systems, which limits their clinical application and makes the combination costly and impracticable. In this work we present and evaluate a compact and ergonomically designed handheld probe, connected to a portable ultrasound system for inexpensive, real-time dual-modality ultrasound/photoacoustic imaging. The probe integrates an ultrasound transducer array and a highly efficient diode stack laser emitting 130 ns pulses at 805 nm wavelength and a pulse energy of 0.56 mJ, with a high pulse repetition frequency of up to 10 kHz. The diodes are driven by a customized laser driver, which can be triggered externally with a high temporal stability necessary to synchronize the ultrasound detection and laser pulsing. The emitted beam is collimated with cylindrical micro-lenses and shaped using a diffractive optical element, delivering a homogenized rectangular light intensity distribution. The system performance was tested in vitro and in vivo by imaging a human finger joint
机译：超声和光声可以用作补充成像技术，以改善临床诊断。光声提供光学对比度和功能信息，而超声提供结构和解剖信息。迄今为止，光声成像使用了大型且昂贵的系统，这限制了它们的临床应用并使该组合昂贵且不可行。在这项工作中，我们介绍并评估了一种紧凑的，符合人体工学原理的手持式探头，该探头连接到便携式超声系统，以进行廉价的实时双模态超声/光声成像。该探头集成了超声换能器阵列和高效二极管堆叠激光器，该激光器在805 nm波长下发射130 ns脉冲，脉冲能量为0.56 mJ，脉冲重复频率高达10 kHz。二极管由定制的激光驱动器驱动，该激光驱动器可以在外部触发，以使超声检测和激光脉冲同步所需的高时间稳定性。发射的光束用圆柱微透镜准直，并使用衍射光学元件定形，从而提供均一的矩形光强度分布。通过对人的手指关节成像在体外和体内测试了系统性能

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